Welcome to the Nucleolar Proteome Database. This
site contains all of the data from our ongoing proteomic analysis
of human nucleoli, which is carried out as a collaboration between
and Mann laboratories (in Denmark
Using high sensitivity mass spectrometry and stringent criteria,
we have so far identified ~700 human nucleolar proteins. More recently,
we used a quantitative proteomic approach for the temporal characterization
of protein flux through the nucleolus, determining the kinetics
of up to 489 nucleolar proteins after various drug treatments and
demonstrating that there is no unique, complete proteome for the
nucleolus, but rather an overlapping set of proteomes that are relevant
to different cell states or conditions. September 19, 2006
The search function of the Nucleolar Proteome Database is currently
disabled while we make some necessary changes to the structure.
In the meantime, you can still download the data in table form.
For a downloadable PDF file listing all of the proteins alphabetized
by name, click here. The
same table is available with the proteins listed by molecular weight
by clicking here.
If you require any further information please feel free to contact